All TPB constructs positively correlated with the intention to use cannabis. Perceived behavioral control was associated with intention among respondents with negative to neutral attitudes towards cannabis (AOR = 2.48, 95% CI 1.63–3.77, p < 0.001), but not among those with positive attitudes. Descriptive norm (standardized coefficient = 0.570) had better explanatory power than the injunctive norm (standardized coefficient = −0.143) in the model. In the final multiple logistic regression model adjusted for age, only attitude (AOR = 1.19, 95% CI 1.13–1.25, p < 0.001) and perceived availability ( p = 0.004) showed statistically significant associations with intention. Respondents with intention had better knowledge of cannabis. Age was the only demographic variable associated with cannabis use intention ( p = 0.029). Nine hundred ninety-six responses were collected, of which 629 were complete and analysed. Responses were obtained from the Faculty of Medicine of a local university. An online cross-sectional survey on cannabis, including validated survey tools and questions on demographics, knowledge, and constructs of the TPB was designed, and distributed during virtual classes in late 2020. This study aimed to understand future healthcare workers' intention to use cannabis through extended Theory of Planned Behavior (TPB). There is a global wave of legalization of recreational and medical cannabis. 3School of Public Health, The University of Hong Kong, Pokfulam, Hong Kong SAR, ChinaĬannabis is the most extensively abused drug, leading to multiple health burdens such as traffic accidents and psychosis.2Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.1The Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.Sze Wing Cherelle Ho 1 *, Yuen Lung WONG 2 and Pui Hong Chung 1,3

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